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Polycarbonate Clear Mouse Handling Tubes

 

Specification:

130 x 50mm ID 3mm wall thickness

100 x 50mm ID 3mm wall thickness (new size coming soon)

 

Product Code:

GZCHTube-130

GZCHTube-100

 

Available in:

Singles

Bulk discounts are available

 

Suitable For:

icons-2-01

 

 

 

 

Made from high temperature
polycarbonate  – autoclavable to 121°c


 

Product Description

 

Research has shown that picking up mice by the tail induces aversion and high anxiety and generally should be avoided. Mice are quick to habituate to tunnel handling and can subsequently be restrained by the scruff or tail base for procedures or health and welfare assessments without negating the positive impacts of the non-aversive capture. To reduce stress and help you gain more accurate results while testing, Datesand have developed reusable 3mm fit for purpose Clear Handling Tubes.

We offer 3 different sized Clear Handling Tubes depending on your needs, including 100mm, 130mm and 110mm clip-on tubes.

 

• Made from 3mm thick clear polycarbonate
• High-Grade Polycarbonate
• Injection Moulded for smoother edges
• 50mm inside diameter
• Reduces handling anxiety and stress
• Makes animal observations easier
• Reduces the risk of being bitten
• Minimal physical contact required
• Autoclavable at 121ºC and cagewasher safe

For information and guidance on tunnel handling of mice, please see the NC3Rs website: www.nc3rs.org.uk/how-to-pick-up-a-mouse

 

Product Care Guidelines

 

Certificate Of Analysis

 

New video tutorial released by NC3R’s: mouse handling made easier

 

Covered by our 1 year warranty

 

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Visit: NC3Rs website to watch video tutorial

 


 

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Visit:  NC3Rs to watch the online webinar

 

 

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Technical Papers

 

Taming Anxiety in Laboratory Mice

 

Jane L Hurst & Rebecca S West

Routine laboratory animal handling has profound effects on their anxiety and stress responses, but little is known about
the impact of handling method. We found that picking up mice by the tail induced aversion and high anxiety, whereas use of tunnels or open hand led to voluntary approach, low anxiety and acceptance of physical restraint. using the latter methods, one can minimize a widespread source of anxiety in laboratory mice.

 

Download Pdf

Mouse handling research papers

Below are links to the original papers which provide the evidence-base for the non-aversive handling methods, as well as papers which validate or use the refined handling techniques.

 

Research papers table:

nc3rs_-_mouse_handling_research_papers_table

 

The original papers:

  • Hurst JL, West RS (2010) Taming anxiety in laboratory mice. Nature Methods 7:825-826. doi:10.1038/nmeth.1500
  • Gouveia K, Hurst JL (2013) Reducing mouse anxiety during handling: Effect of experience with handling tunnels. PLoS ONE 8(6): e66401. doi:10.1371/journal.pone.0066401
  • Gouveia K, Hurst JL (2017) Optimising reliability of mouse performance in behavioural testing: the major role of non-aversive handling. Scientific Reports 7: 44999. doi:10.1038/srep44999

Papers that validate the improved handling techniques:

  • Ghosal S et al. (2015) Mouse handling limits the impact of stress on metabolic endpoints. Physiology and Behaviour 150:31-37. doi:10.1016/j.physbeh.2015.06.021
  • Clarkson JM, Dwyer DM, Flecknell PA, Leach MC, Rowe C (2017) Handling method alters the hedonic value of reward in laboratory mice. Scientific Reports 8: 2448. doi:10.1038/s41598-018-20716-3
  • Nakamura Y, Suzuki K (2018) Tunnel use facilitates handling of ICR mice and decreases experimental variation. J Vet Med Sci 80(6): 886-892. doi:10.1292/jvms.18-0044